Diffusimax is pluronic lecithin organogel, often abbreviated as PLO gel. It is a liposomal base that is used as a vehicle for preparing a wide range of topical formulations. Diffusimax and Diffusimax10 Pre-Mixed Creams and Diffusimax and Diffusimax10 Kits do not contain active ingredients; medications are added by a pharmacist as prescribed by a physician. The medications most commonly used in Diffusimax are the non-steroidal anti-inflammatory drugs, but many different medications and combinations of medications are now being prescribed. Refer to the compounding instructions for a listing of drugs and drug combinations used in Diffusimax.
At the Pharmacy: Diffusimax Pre-Mixed Cream should be stored at room temperature. For Diffusimax Kits, the lipophilic (Compound A) component is stored at room temperature. The hydrophilic (Compound B) component can be stored at room temperature, but must be put into the refrigerator prior to mixing to allow it to liquefy. Many pharmacists refrigerate the B component until it is required for preparing cream.
Diffusimax that has been compounded with medication should be stored at room temperature.
Patients: should store their prescriptions at room temperature.
The shelf life for all unopened Diffusimax products is 5 years from the date of manufacture.
The Beyond-Use Date (BUD) for a compounded prescription is the lesser of the expiry date of the incorporated drug or the BUD for the compounded medication (See BUD List), as long as this is within the 5-year shelf life of the Diffusimax Pre-Mixed cream or the Diffusimax Kit.